Last updated: 2023-11-20

Checks: 6 1

Knit directory: multigroup_ctwas_analysis/

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Top five tissues

head(num_weights,5)
                 tissue number of weights
43              Thyroid              2341
42               Testis              2240
1  Adipose_Subcutaneous              2057
25     Esophagus_Mucosa              2056
30                 Lung              2055

Last five tissues

tail(num_weights,5)
                                 tissue number of weights
15                   Brain_Hypothalamus               268
14                    Brain_Hippocampus               211
8  Brain_Anterior_cingulate_cortex_BA24               208
18       Brain_Spinal_cord_cervical_c-1               194
7                        Brain_Amygdala               125

Adipose_Subcutaneous

results[["Adipose_Subcutaneous"]][["group_pve"]]
         SNP         gene 
0.0684186051 0.0003157631 
results[["Adipose_Subcutaneous"]][["top_genes"]]
                                 id susie_pip
373346        NM_001908|CTSB|chr8|- 0.6739060
737980       NM_014248|RBX1|chr22|+ 0.4111174
741598 NR_037640|HEATR8-TTC4|chr1|+ 0.4084906
529313      NM_018457|PRR13|chr12|+ 0.4004120
271829       NM_022754|SFXN1|chr5|+ 0.3738829

Adipose_Visceral_Omentum

results[["Adipose_Visceral_Omentum"]][["group_pve"]]
         SNP         gene 
0.0733057330 0.0003479959 
results[["Adipose_Visceral_Omentum"]][["top_genes"]]
                            id susie_pip
738212  NM_014248|RBX1|chr22|+ 0.5716242
289590   NM_000287|PEX6|chr6|- 0.5493644
123118  NM_014160|MKRN2|chr3|+ 0.5143896
736925 NM_030882|APOL2|chr22|- 0.5038247
467148 NM_015631|TCTN3|chr10|- 0.4559593

Lung

results[["Lung"]][["group_pve"]]
         SNP         gene 
6.896433e-02 2.152813e-05 
results[["Lung"]][["top_genes"]]
                                id  susie_pip
302137 NM_001168398|SLC35A1|chr6|+ 0.18840850
81522       NM_000542|SFTPB|chr2|- 0.14079800
737356     NM_030882|APOL2|chr22|- 0.09186556
265111     NM_205836|FBXO38|chr5|+ 0.09130455
700610    NM_005628|SLC1A5|chr19|- 0.06109755

Liver

results[["Liver"]][["group_pve"]]
         SNP         gene 
0.0731320284 0.0003870427 
results[["Liver"]][["top_genes"]]
                            id susie_pip
289005   NM_000287|PEX6|chr6|- 0.7966261
373173   NM_001908|CTSB|chr8|- 0.7774279
740747    NM_000379|XDH|chr2|- 0.7661409
352168 NM_015395|TECPR1|chr7|- 0.6405067
286012   NM_000544|TAP2|chr6|- 0.6191271

Whole_Blood

results[["Whole_Blood"]][["group_pve"]]
         SNP         gene 
0.0667958155 0.0009569112 
results[["Whole_Blood"]][["top_genes"]]
                              id susie_pip
743863 NM_001136033|PUF60|chr8|- 0.9840494
748229   NM_016320|NUP98|chr11|- 0.9747243
766126    NM_014248|RBX1|chr22|+ 0.8872658
741442     NM_006908|RAC1|chr7|+ 0.8722609
289203     NM_000287|PEX6|chr6|- 0.7749128

sessionInfo()
R version 4.1.0 (2021-05-18)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: CentOS Linux 7 (Core)

Matrix products: default
BLAS/LAPACK: /software/openblas-0.3.13-el7-x86_64/lib/libopenblas_haswellp-r0.3.13.so

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] cowplot_1.1.1     ggplot2_3.4.0     RSQLite_2.2.19    data.table_1.14.6
[5] workflowr_1.7.0  

loaded via a namespace (and not attached):
 [1] Rcpp_1.0.9       lattice_0.20-44  getPass_0.2-2    ps_1.7.2        
 [5] assertthat_0.2.1 rprojroot_2.0.3  digest_0.6.31    foreach_1.5.2   
 [9] utf8_1.2.2       R6_2.5.1         evaluate_0.19    httr_1.4.4      
[13] pillar_1.8.1     rlang_1.1.1      rstudioapi_0.14  whisker_0.4.1   
[17] callr_3.7.3      jquerylib_0.1.4  blob_1.2.3       Matrix_1.3-3    
[21] rmarkdown_2.19   labeling_0.4.2   stringr_1.5.0    bit_4.0.5       
[25] munsell_0.5.0    compiler_4.1.0   httpuv_1.6.7     xfun_0.35       
[29] pkgconfig_2.0.3  htmltools_0.5.4  tidyselect_1.2.0 tibble_3.1.8    
[33] logging_0.10-108 codetools_0.2-18 ctwas_0.1.40     fansi_1.0.3     
[37] dplyr_1.0.10     withr_2.5.0      later_1.3.0      grid_4.1.0      
[41] jsonlite_1.8.4   gtable_0.3.1     lifecycle_1.0.3  DBI_1.1.3       
[45] git2r_0.30.1     magrittr_2.0.3   scales_1.2.1     cli_3.6.1       
[49] stringi_1.7.8    cachem_1.0.6     farver_2.1.0     fs_1.5.2        
[53] promises_1.2.0.1 pgenlibr_0.3.2   bslib_0.4.1      vctrs_0.6.3     
[57] generics_0.1.3   iterators_1.0.14 tools_4.1.0      bit64_4.0.5     
[61] glue_1.6.2       processx_3.8.0   fastmap_1.1.0    yaml_2.3.6      
[65] colorspace_2.0-3 memoise_2.0.1    knitr_1.41       sass_0.4.4